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File #: 25-397    Name:
Type: Staff Report Status: Public Hearing
File created: 4/14/2025 In control: City Council
On agenda: 6/25/2025 Final action: 6/25/2025
Title: Report regarding consideration of Genentech's acquisition of certain public rights-of-way within the Genentech Campus, proposed rezoning of private properties to be added to the Genentech Master Plan District, associated amendments to the General Plan, Genentech Campus Master Plan, and Zoning Map and finding that the 2025 Addendum is the appropriate environmental document for the Project, per CEQA Guidelines Section 15162 (Billy Gross, Principal Planner).
Attachments: 1. Att 1 - Genentech Project Description, 2. Att 2 - Planning Commission Minutes, 3. Att 3a - PC CEQA Resolution, 4. Att 3b - PC Entitlements Resolution, 5. Att 4 - PC Comment Letters, 6. SB 343 -Att 5 – San Mateo County ALUC Resolution, 7. Att 6 - Staff Presentation, 8. SB 343 Item 8b - Genentech Presentation 6.25.25
Related files: 25-398, 25-399, 25-400, 25-401, 25-644
Title
Report regarding consideration of Genentech's acquisition of certain public rights-of-way within the Genentech Campus, proposed rezoning of private properties to be added to the Genentech Master Plan District, associated amendments to the General Plan, Genentech Campus Master Plan, and Zoning Map and finding that the 2025 Addendum is the appropriate environmental document for the Project, per CEQA Guidelines Section 15162 (Billy Gross, Principal Planner).

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RECOMMENDATION
Recommendation
Staff recommends that the City Council conduct a public hearing, follow the recommendation of the Planning Commission and take the following actions:
1. Adopt a resolution making findings and a determination that, based on the 2025 Addendum, the project is consistent with the adopted Genentech Master Plan Environmental Impact Report and the adopted SSF 2040 General Plan Update, Zoning Code Amendments, and Climate Action Plan Environmental Impact Report, and approval of the project would not necessitate the need for preparing a subsequent environmental document pursuant to the criteria of CEQA Guidelines Section 15162.
2. Adopt a resolution making findings and approving the street vacations of certain public rights-of-way commonly known as DNA Way, Cabot Road, and Point San Bruno Boulevard located entirely within the Genentech Campus.
3. Adopt a resolution approving the sale of DNA Way, Point San Bruno Boulevard and a portion of Cabot Road to Genentech in the sum of $25,000,000 and associated Purchase and Sale Agreement memorializing such sale and authorizing the City Manager to execute the Purchase and Sale Agreement.
4. Waive reading and introduce an Ordinance amending the South San Francisco Zoning Map to include additional properties within the Genentech Master Plan District.
5. Adopt a resolution making findings and approving a General Plan Amendment and Genentech Campus Master Plan Amendment.

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EXECUTIVE SUMMARY
Genentech established its headquarters in So...

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